Altered intercellular communication as a hallmark of aging is like a breakdown in the communication system between different parts of a team.

In our bodies, cells need to communicate with each other to coordinate various functions and maintain overall health. This communication is essential for tasks like responding to injuries, fighting off infections, and regulating our body’s functions.

As we age, the ways in which cells communicate can become less efficient or disrupted, much like how team members might stop sharing important information with each other. This breakdown in communication can lead to problems in coordinating the body’s responses to various challenges, such as healing injuries or defending against diseases.

So, altered intercellular communication in aging means that the “teamwork” between cells becomes less effective or misaligned, potentially contributing to the aging process and age-related health issues.